Alcohols and polyols
- (1)
- (55)
- (350)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
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- (155)
- (1)
- (63)
- (29)
- (14)
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- (1)
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- (30)
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- (20)
- (10)
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- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
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- (1)
- (1)
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- (21)
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- (2)
- (1)
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- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
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- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
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- (1)
- (3)
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- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
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- (1)
- (1)
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- (1)
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- (1)
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Defactinib hydrochloride is the hydrochloride salt of defactinib (VS-6063; PF-04554878), a small-molecule focal adhesion kinase (FAK) inhibitor used in research to study FAK signaling, tumor cell motility, and antineoplastic and antiangiogenic mechanisms.
- Inhibits FAK phosphorylation at Tyr397 in a time- and dose-dependent manner.
- Hydrochloride salt form, off-white powder suitable for research use.
- Molecular formula C20H22ClF3N8O3S; molecular weight 546.95 g/mol.
- Reported purity 99.35% with available certificate of analysis.
- Available in multiple pack sizes, including 50 mg.
- Supporting documents available: data sheet, COA, and SDS.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Proadifen (hydrochloride) | 62-68-0 | 99.95% | 1 ML
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Proadifen hydrochloride, also known as SKF-525A, is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. It reduces monoamine oxidase A activity and N,N-dimethyltryptamine metabolism. This compound is promising for research related to metabolism-related diseases, ovarian carcinoma, inflammation, and dopamine neuron-related diseases.
- Reduces monoamine oxidase A activity
- Reduces N,N-dimethyltryptamine metabolism in liver microsomes
- Inhibits N-demethylation and Acridone formation
- Augments lipopolysaccharide-induced fever
- Exacerbates prostaglandin E2 levels in rats
- Promising for research of metabolism-related diseases
- Promising for research of ovarian carcinoma
- Promising for research of inflammation
- Promising for research of dopamine neuron-related diseases
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Imidapril (hydrochloride) | 89396-94-1 | 99.9% | 50 MG
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Imidapril hydrochloride (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. It suppresses the conversion of angiotensin I to angiotensin II, reducing total peripheral resistance and systemic blood pressure. It is used for research related to hypertension, type 1 diabetic nephropathy, and chronic heart failure.
- Orally active ACE inhibitor
- MMP-9 inhibitor
- Suppresses angiotensin I to angiotensin II conversion
- Reduces total peripheral resistance
- Reduces systemic blood pressure
- Used for hypertension research
- Used for type 1 diabetic nephropathy research
- Used for chronic heart failure research
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Medchemexpress LLC Pociredir hydrochloride | 2490676-19-0 | 99.9% | 439.87 | 10 MM/1 ML
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Pociredir hydrochloride, also known as FTX-6058, is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). It is utilized in research for select hemoglobinopathies like sickle cell disease and β-thalassemia by inducing HbF protein expression in cell and murine models.
- Potent and orally active inhibitor of EED
- Induces HbF protein expression in cell and murine models
- Used in research for select hemoglobinopathies, including sickle cell disease and β-thalassemia
- Inhibits PRC2 via binding to EED
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Medchemexpress LLC Amelparib hydrochloride | 98.4% | 379.88 | C19H26ClN3O3 | 5 MG
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Amelparib hydrochloride is the hydrochloride salt form of a PARP-1 inhibitor used as a research reagent to investigate DNA damage response and PARP-related pathways. It is supplied as a high-purity solid suitable for biochemical and cellular assays.
- Potent PARP-1 inhibitor activity
- Hydrochloride salt for improved water solubility
- High purity (98.4%)
- Molecular weight 379.88 g/mol
- Suitable for biochemical and cellular research applications
- Supplied as a 5 mg solid package
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Medchemexpress LLC Naluzotan hydrochloride | 740873-82-9 | 99.6% | 487.10 g/mol | C23H39ClN4O3S | 10 MG
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Naluzotan hydrochloride is the hydrochloride salt of a potent, selective amidosulfonamide 5-HT1A receptor agonist used in preclinical research. It is supplied as a solid research chemical with characterized purity and analytical data, intended for laboratory use only.
- High purity (99.6%) suitable for research applications.
- Potent, selective 5-HT1A receptor agonist (IC50 ≈ 20 nM; Ki ≈ 5.1 nM).
- Weak hERG K+ channel blocker (IC50 ≈ 3,800 nM), relevant for cardiac safety studies.
- Solid form; molecular weight 487.10 g/mol; formula C23H39ClN4O3S.
- Supplied in a 10 mg research pack and for research use only.
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Medchemexpress LLC Leonurine hydrochloride | 24735-18-0 | 347.79 | 100 MG
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Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, exhibiting anti-oxidative and anti-inflammatory properties. This compound is intended for research use only, playing a role in various biological activities in vitro and in vivo.
- Causes diminution in lipid accumulation and cellular cholesterol content.
- Increases apoA-I- or HDL-mediated cholesterol efflux.
- Significantly increases the expressions of ABCA1 and ABCG1.
- Shows protective effects on cell viability of HepG2 and HL-7702 cells.
- Improves cellular lipid accumulation via activating AMPK/SREBP1 pathway.
- Inhibits the expression of iNOS, COX-2, PGE2, NO, TNF-α, and IL-6.
- Suppresses ECM degradation in human OA chondrocytes.
- Blocks IL-1β-induced PI3K and Akt phosphorylation.
- Ameliorates osteoarthritis development in mouse DMM model.
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Medchemexpress LLC Simufilam hydrochloride (PTI-125 hydrochloride) | 2480226-07-9 | 99.9% | 295.81 | 25 MG
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Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. It restores NMDAR signaling and Arc expression. It inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation, and tau protein hyperphosphorylation. This product can be used for research related to Alzheimer's disease.
- Reduces FLNA-α7nAChR/TLR4 associations and dissociates Aβ42-α7nAChR complexes.
- Restores α7nAChR/NMDAR/IR function and NMDAR signaling and arc expression in human AD brain slices.
- Decreases tau phosphorylation, Aβ42 aggregates, and inflammatory cytokines in mouse models.
- Improves NMDAR/IR function, synaptic plasticity, spatial/working memory, and nesting behavior in 3xTg AD mice.
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Medchemexpress LLC RIBOCICLIB HYDROCHLO 10MM 1ML
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RIBOCICLIB HYDROCHLO 10MM 1ML
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Medchemexpress LLC GRP-60367 HYDROCHLO 100 mg
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GRP-60367 HYDROCHLO 100MG
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Medchemexpress LLC PDK4-IN-1 HYDROCHLO 25 mg
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PDK4-IN-1 HYDROCHLO 25MG
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Medchemexpress LLC SB-505124 HYDROCHLO 100 mg
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SB-505124 HYDROCHLO 100MG
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Medchemexpress LLC AP-III-A4 HYDROCHLO 10MM 1ML
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AP-III-A4 HYDROCHLO 10MM 1ML
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Medchemexpress LLC AP-III-A4 HYDROCHLO 100 mg
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AP-III-A4 HYDROCHLO 100MG
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Medchemexpress LLC ENPATORAN HYDROCHLO 200 mg
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ENPATORAN HYDROCHLO 200MG
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